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FurinproteaseinhibitorsforthetreatmentofHIV-1andtheirpreparationmethod

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Registration number：G20250526

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Key words： Furin enzyme inhibitor Green bean trypsin

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Publisher：管理人员

Release time：2025-08-09 08:54:54.0

  • Essential information
Name of achievement： FurinproteaseinhibitorsforthetreatmentofHIV-1andtheirpreparationmethod
Result registration number： G20250526 Subject classification：
Green classification： Item keywords： Furin enzyme inhibitor  Green bean trypsin      
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Tongji University

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Countries/regions： China Intellectual property rights：
Introduction： Click to view
The purpose of this invention is to provide an anti-HIV-1 inhibitor with a small molecular weight and high activity. Based on the original mung bean trypsin inhibitor fragment, this invention changes certain characteristic amino acids, obtains the required crude peptide sample by synthetic methods, and finally achieves a highly pure sample through stepwise reduction-oxidation techniques. It has been proven that it possesses the effect of a furin enzyme inhibitor, providing a new approach for the treatment of AIDS.
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