One of the key technologies for bone repair materials is to prepare biomaterials with good biocompatibility, biodegradability, and absorbability into porous cell scaffolds with specific shapes and three-dimensional connectivity. The 45S5 bioactive glass based on silicate, which has been clinically applied, possesses certain osteoinductive properties. However, the silicon element is difficult to degrade within the body, and this type of glass is challenging to process into high-strength bone tissue engineering scaffolds. In the early stage, a borate-based fully biodegradable borate glass was developed by the School of Materials Science and Engineering at Tongji University. It can be made into large-pore sponge-like structures with high mechanical strength and possesses both biocompatibility and complete, controllable biodegradability. This material can be used as a scaffold for tissue engineering activated by cells or genes, implanted into the body, and can adapt to the growth rate requirements of bone tissues in different clinical locations. The degradation rate can be controllably adjusted, and it can eventually be completely degraded, possessing various characteristics of third-generation biomaterials. Preliminary results from animal experiments conducted by the Affiliated Shanghai Sixth People's Hospital of Shanghai Jiao Tong University have shown and confirmed that this material meets the needs of clinical bone repair and bone replacement materials.