This project belongs to the field of traditional Chinese medicine orthopedics. Main content: Based on the understanding of the key pathogenesis of cervical spondylosis in traditional Chinese medicine, namely 'bone misalignment and tendon out of groove', systematic research has been conducted on its diagnosis and treatment techniques, resulting in the following innovative achievements. (1) The connotation and extension of 'bone misalignment and tendon out of groove' have been clearly defined: Through theoretical sorting and literature research, it is proposed that 'bone misalignment and tendon out of groove' refers to a pathological state where there are subtle abnormal changes in the normal intervertebral space or relative position of the bones, as well as in the morphology, structure, and spatial position of the tendons, which cause limited range of motion in the corresponding joint movement units. (2) A clinical assessment technical scheme for cervical 'bone misalignment and tendon out of groove' has been constructed: By integrating four core elements including clinical symptoms, routine signs of cervical spondylosis, special signs, and imaging measurements, Assessment from both 'structural' and 'functional' abnormalities can achieve qualitative, positional, and directional diagnosis of cervical 'bone misalignment with tendon dislocation', providing an accurate 'target point' for manual correction. (3) The clinical effectiveness and safety of the technique for correcting 'bone misalignment with tendon dislocation' in treating cervical spondylosis have been confirmed: Through three different types of clinical trials, repeatability verification results confirm that the technique for correcting 'bone misalignment with tendon dislocation' can effectively restore the positional relationship of the atlantoaxial joint, mid-segment and lower segment facet joints in the cervical spine. (4) The diagnosis and treatment technology for cervical 'bone misalignment with tendon dislocation' has good promotability: Through multiple clinical trials, A study on the clinical assessment techniques and manual correction methods for 'bone misalignment and tendon dislocation' of cervical spine has been carried out, showing good promotability. Project Characteristics: Focusing on the understanding of the pathogenesis of 'bone misalignment and tendon dislocation' in cervical spine, a systematic and comprehensive research has been conducted from theory to application, from clinical assessment to manual treatment techniques, from evaluation of clinical effectiveness and safety to wider application promotion, resulting in clear outcomes. Application Promotion: The diagnosis and treatment technology for 'bone misalignment and tendon dislocation' of cervical spondylosis has been promoted nationwide as a characteristic diagnostic and treatment technique by the National Administration of Traditional Chinese Medicine, and has been promoted throughout the city as a key project by the Shanghai Shenkang Hospital Development Center (with promotion assessment results of 'excellent'). It has also been promoted through the organization of continuing education classes, media publicity, and other forms. Six national continuing education classes have been held (training over 800 personnel), and five lectures were given in the media. CCTV-4's 'Chinese Medicine' program reported on this project twice, on February 3, 2010, and July 27, 2012. The technologies involved in this project have been used in more than a dozen medical institutions such as Shanghai Yueyang Hospital, Guangdong Second Traditional Chinese Medicine Hospital, and Shanghai Sixth People's Hospital. The achievements involved in this project include: training 12 graduate students (3 doctoral and 9 master's), publishing 104 papers, co-authoring or participating in the compilation of 30 textbooks and monographs, applying for 7 patents (including 3 invention patents), and obtaining 6 patents (including 2 invention patents), with 102 citations in articles.